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By National Research Council, Division on Earth and Life Studies, Board on Environmental Studies and Toxicology, Board on Chemical Sciences and Technology, Committee on the Design and Evaluation of Safer Chemical Substitutions: A Framework to Inform Governme

ISBN-10: 030931013X

ISBN-13: 9780309310130

ISBN-10: 0309310148

ISBN-13: 9780309310147

Traditionally, laws governing chemical use have frequently taken with customary chemical substances and acute human well-being results of publicity to them, in addition to their strength to reason melanoma and different antagonistic wellbeing and fitness results. As medical wisdom has multiplied there was an elevated wisdom of the mechanisms during which chemical compounds could exert destructive results on human healthiness, in addition to their results on other  Read more...

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Additional expertise in engineering, epidemiology, social sciences, economics, and cost analysis may also be required. Assessors without such expertise, such as small- and medium-sized firms, may need user-friendly assessment tools or technical support to carry out parts of the committee’s framework.  The framework should provide maximum flexibility to the user while identifying critical steps that should be retained in all alternatives assessments.  The framework should not be overly prescriptive by specifying all steps or tools needed to conduct an alternatives assessment.

According to the Business-NGO Working Group, such businesses are not invested in the use of any particular chemical but rather tend to focus on the function the chemicals provide to achieve product performance (Rossi et al. 2012). The BizNGO CAA protocol (Rossi et al. 2012) is based around a 7-step decision tree. The BizNGO CAA protocol recommends ordered steps for carrying out an alternatives assessment without prescribing how to carry out each step (OECD 2013a). For example, the protocol includes life cycle assessment and risk assessment as two separate steps, noting that they are not always necessary or appropriate for selecting an alternative (OECD 2013a).

According to Malloy (Malloy et al. 2011), the results demonstrate that the models can produce a transparent evaluation that ranks alternatives and explains how the alternatives’ performance on various criteria affected their ordering. The models also allow the methods’ assumptions to be adjusted (Malloy et al. 2011). fate (BizNGO, EPA DfE, German Guide, IC2, REACH, TURI, UCLA MCDA, UNEP) and ecotoxicity (BizNGO, CA SCP, EPA DfE, IC2, REACH, TURI, UCLA MCDA, UNEP) in their analyses. Some, but not all, frameworks consider life cycle analysis (or Life Cycle Thinking depending upon the framework; see Chapter 10 for a description of Life Cycle Thinking) and the chemical’s functional use or application.

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A framework to guide selection of chemical alternatives by National Research Council, Division on Earth and Life Studies, Board on Environmental Studies and Toxicology, Board on Chemical Sciences and Technology, Committee on the Design and Evaluation of Safer Chemical Substitutions: A Framework to Inform Governme


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