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By E. B. Smith, S. Björkerud, R. H. More, D. Sinapius, G. S. Berenson, W. Insull (auth.), G. Schettler, A. Weizel (eds.)

ISBN-10: 3642659543

ISBN-13: 9783642659546

ISBN-10: 364265956X

ISBN-13: 9783642659560

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Of twe forms. of a circle with a black Formee cross with quadrants of yellow and blue. Isotrepic forms true liquids, are grey (Lang and Insull, 1970). In fatty streaks the propertion of anisetrepic forms is higher than in fibreus plaques. 11 Chemical analyses of the lipids show that cholesterol ester is the dominant lipid, 81% of total lipids in fatty streaks, and 59% of total lipid in fibrous plaques. The proportions of ester and other lipids are distinctly different for the fatty streak and fibrous plaque inclusions (Table 1)(Insull, 1972).

He is the one to benefit from it, by elimination of risk factors or by a change of unhealthy habits. In addition, the example of the individual is of educational value. We should turn to the young people and familiarize them with practical problems of atherosclerosis research through the curricula of high schools and universities. This is an ambitious program. It can only be accomplished one step at a time. But a great goal is worth such world-wide efforts. International co-operation in medical science is needed now.

These are: I. MPS are highly charged, reactive macromolecules capable of trapping water, binding electrolytes and ions, such as Ca++. 2. MPS have an inter-relationship with the fibrous structures--collagen, elastin. 3. The amount and composition of MPS vary in different sites in the aorta. For ~Supported by funds from USPHS and NHLI (HLISI03-HL02942) and the American Heart Association. 6 AORTIC MPS VARIATIONS WITH EXTENT OF ATHEROSCLEROSIS AND TYPE OF LESION ! :! c u u ~ 0 D. E ~ o 10 20 30 40 50 60 Percent Totel Surfece Involvement Figure I.

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Atherosclerosis III: Proceedings of the Third International Symposium by E. B. Smith, S. Björkerud, R. H. More, D. Sinapius, G. S. Berenson, W. Insull (auth.), G. Schettler, A. Weizel (eds.)


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