By National Research Council (U. S.)
By National Research Council (U. S.)
By Curtis Klaassen
A Doody's center name for 2015!
NEW to the 8th Edition
The world's top and such a lot authoritative textbook on poisons has extra to supply students,toxicologists, and pharmacologists than ever prior to. Now in complete colour, and punctiliously revised, the 8th version of Casarett & Doull's TOXICOLOGY: the fundamental technology of Poisons not just promises a accomplished evaluate of the fundamental parts of toxicology, it bargains the main up-to-date,revealing, and in-depth examine the systemic responses of poisonous substance on hand anywhere.
Combined with the most recent pondering via the field's greatest students plus reliable assurance of normal rules, modes of motion, and chemical-specific toxicity, this landmark textual content maintains to set the normal for toxicology references.
By Michael E. Peterson DVM MS, Patricia A. Talcott MS DVM PhD DipABVT
Diagnose and verify remedy for poisonous exposures in small animals with this quickly reference! Small Animal Toxicology, third Edition covers hundreds and hundreds of probably poisonous elements, offering the knowledge you want to deal with emergency therapy and forestall poisonings in better half animals. that can assist you establish an unknown poison, this consultant presents a listing of power pollution in keeping with medical indicators or signs. it's also a brand new colour insert with eighty five full-color pictures of poisonous crops and of lesions linked to quite a few poisonings. Written via revered veterinarian Michael E. Peterson and board-certified veterinary toxicologist Patricia A. Talcott, besides a staff of professional participants, this variation covers a wide selection of themes together with toxicodynamics, toxicokinetics, potent background taking, spotting medical indicators of poisonous exposures, coping with emergencies, and supportive care of the poisoned patient.
contains the whole diversity of drugs from acetaminophen to zinc, together with domestic items, prescription medications, leisure medicines, and extra.
cover themes together with criminal issues in toxicology instances, responding to mass exposures, and poisonings in birds, small mammals, and geriatric patients.
By Robert L. Harris
The traditional reference in occupational healthiness and safeguard for over 50 years, the recent Patty's offers for the 1st time a separation of business hygiene and toxicology subject matters, delivering entire reorganization of the cloth into 4 volumes of basically outlined subject components.
By W. Norman Aldridge
Makes a speciality of examine techniques in toxicology, aiming to demonstrate strategies and kinds of toxicity from a mechanistic viewpoint. Examples of chemical intoxicants are used to demonstrate mechanisms in every one degree of toxicity.
By Mark T D Cronin; Judith C Madden
Content material: advent; part 1: Compiling the version; assets of Toxicity facts for In Silico Toxicology; Calculation of Physico-Chemical houses; Calculation of Theoretical 2-D Descriptors; Calculation of Molecular Orbital Descriptors; QSAR tools: Receptor Modelling in Toxicology; comparing facts caliber; part 2: information Integration, research and Utilisation; QSAR tools: Statistical Methodologies; Characterisation, review and attainable Validation of a QSAR; Applicability area Mechanisms of poisonous motion in In Silico Toxicology; Formation of different types; Read-Across Endpoint-Based Extrapolation; function of publicity in Modelling; specialist platforms instruments for type Formation and Read-Across; part three: program of In Silico Toxicology to threat review; Weight of facts in Toxicity Prediction; built-in checking out innovations; Case research: Predicting Environmental Toxicity; Case research: Predicting Human well-being; In Silico Toxicology in danger evaluate
By Ramesh C. Gupta
This text/reference e-book presents the main entire assurance of anticholinesterase compounds (Organophosphates and Carbamates), which represent the biggest variety of chemical compounds which are basically used as pesticides in agriculture, undefined, and round the home/garden. a few OPs (nerve brokers) were utilized in chemical conflict and terrorist assaults, whereas a few OPs and CMs were prompt as healing brokers in human drugs in addition to in veterinary drugs. Many chemical substances of either sessions are tremendous poisonous and shortage selectivity, therefore their inadvertent/accidental use maintains to pose a risk to human and animal future health, aquatic platforms and natural world. those anticholinesterase brokers produce numerous toxicological results in aim and nontarget organs. In gentle of this complexicity, this multi-authored booklet is written through the well-known scientists from many nations. The e-book is equipped into 9 sections, with a complete of forty nine chapters, to supply in-depth wisdom on a variety of features of OP and CM compounds, together with their use, class, mechanism-based toxicity, and prophylactic and healing measurements. numerous chapters are written with precise emphasis to hide well timed subject matters, resembling chemical conflict brokers, physiologically-based pharmacokinetic modeling, constitution and serve as of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative pressure, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with five chapters is in particular dedicated to possibility evaluate, and protection and regulatory directions for insecticides. -Describes every little thing you want to learn about Organophosphates and Carbamates-Extensively covers insecticides, nerve brokers, healing medications, and flame retardants-Describes epidemiology of the world's significant failures regarding Organophosphates and Carbamates-Covers animal, human, aquatic, and natural world toxicity of Anticholinesterases-Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity-Describes contemporary developments in cholinesterases, paraoxonases, carboxylesterases, oxidative pressure, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis-Provides in vitro and in vivo versions for neurotoxicity testing-Integrates wisdom of experiences in lab animals and humans-Offers risk/safety review and national/international guidance for permissible degrees of pesticide residues-Describes administration of Anticholinesterase poisoning in people
By Jerald Silverman
Praise for the former Editions
"The writer brings in administration knowledge from the area outdoor laboratory animal drugs and veterinary medication. for that reason, there's a wealthy mix of the event of a pro specialist and the theoretical framework utilized by colleges of administration …. i like to recommend this booklet to managers and laboratory animal experts at any level in their careers."
―Franklin M. Loew, DVM, PhD, DACLAM, JAVMA, Vol. 222, No. 6, 2003
"… This e-book is an efficient informational source for any new supervisor to the sector of laboratory administration. the data is gifted in a fashion that may retain your curiosity and stimulate you to imagine the way it can profit you and the ability during which you work."
―Susan ok. Cutter, BS, RVT, RLATG, Purdue collage, West Lafayette, Indiana, united states, LAMA Review
Written in Jerry Silverman’s trademark sort, Managing the Laboratory Animal Facility, 3rd variation provides the reader with sound administration idea and linked administration practices which are effortless to learn, effortless to appreciate, effortless to enforce, and pertinent to the day-by-day administration and management of laboratory animal amenities. retaining the sensible concentration of earlier variants, this significantly extended quantity offers the severe wisdom had to assist you make effective and powerful use of the foremost assets which are used each day by way of vivarium managers – humans, time, cash, and information.
New to the 3rd Edition
Incorporating the newest advancements in administration concept and alertness, the variation includes nearly a hundred pages of latest and improved fabric. This extra targeted coverage:
By J Sofos
By Areej Hassan
This selection of well timed chapters offers a nuanced learn of environmental pollutants and the hazards they pose to kid's improvement. The booklet information the impression of a couple of standard environmental pollutants, targeting daily publicity to tobacco smoke, lead, insecticides, and flame retardants. there's transforming into reputation that the influence of our environment on kid's future health is of severe significance for both present and destiny generations. within the final half-century, millions of chemical compounds were brought into the surroundings with limited-although growing-research at the consequence. �Read more...