Kaplan Schweser's CFA Level 3, Schweser Seminar Slide Workbook, Volume 1, 2010 PDF

By Kaplan Schweser

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Additional info for CFA Level 3, Schweser Seminar Slide Workbook, Volume 1, 2010

Example text

The latter are also observable in grayish pocks. 1 mm. After 72 h, the number of pocks increases dramatically doe to development of secondary pocks, similar in density but smaller in size, around the primary pocks. 1). The differences are related to the presence of two different subpopulations of the virus within the population in the latter case. The death of the embryos caused by generalized infection occurs after 56-120 h. Pock-like lesions are observed on the embryo surface; necrotic foci, in the liver, spleen, and kidneys.

According to the data of Tulman et al. (2002), the isolate recovered from the horse and named horsepox virus is rather close to several vaccine strains in its genomic structure. However, as we see it, an insufficiency of the available data yet prevent from speaking definitely about the nature and origin of this virus. The results reported by Bryant et al. (2000), who studied three strains isolated during outbreaks in a colony of white mice in Poland in 1986 and 1988, were quite unexpected. Initially, these strains were erroneously attributed to ectromelia virus.

Probably, Noyes (1953) was the first to report the plaque-forming ability of vaccinia virus. Later, Mika and Pirsch (1960) showed that this ability also manifested itself in cell cultures under agar overlay. They also, like other authors (Porterfield & Allison, 1960; Solov'ev & Bektemirov, 1962; Gurvich & Marennikova, 1964; Mal'tseva, 1965) paid attention to the differences between vaccinia and variola viruses in plaque sizes and times of their development. 95 mm. 2. As with CAM inoculation (formation of white and grayish superficial pocks), various vaccinia virus strains form two plaque types in cell cultures: transparent and reticular (Gendon & Chernos, 1963; Gurvich, 1964; Mal'tseva, 1965).

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CFA Level 3, Schweser Seminar Slide Workbook, Volume 1, 2010 by Kaplan Schweser


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